Bacteriostatic agents and fungicidesCANdot Series D – Nanoparticles with antimicrobial properties

Application of antimicrobial nanoparticles as surface coatings of large areas, for example in clinical environments is a promising approach to suppress bacterial contamination with dangerous pathogenic species like Staphylococcus aureus or Pseudomonas aeruginosa.

A further application area of these nanoparticles is pipelines in food industry, in order to prevent formation of noxious biofilms.

In many fields microorganisms like Staphylococcus aureus and Pseudomonas aeruginosa constitute a serious problem, notably in clinical environments because they colonize on many surfaces, e.g. medical equipment, like catheters. In Europe these microbes cause three million hospital acquired infections, 50000 of them fatal (status 2005). An additional huge problem in this context is the continuously increasing resistance of bacteria against antibiotics. Bacteriostatic nanoparticle based surface coatings have the potential to inhibit cell proliferation and thus could significantly help to decrease the number of hospital acquired infections.

A further problem is the accumulation of microorganisms in biofilms (consisting e.g. of bacteria, protozoa, algae or fungi and their extracellular products), which grow on interfaces where aqueous fluids are in contact with air or solid phases. This process is called biofouling and poses a big issue in the food processing industry, heat exchangers as well as ship hulls amongst many others.

CAN GmbH currently examines the applicability of nanoparticles with antimicrobial properties in this field. If you are interested in a cooperation regarding this question please contact us.


Dr. Vesna Aleksandrovic-Bondzic

Dr. Vesna Aleksandrovic-Bondzic